PARADIGM BYTES
Newsletter for Paradigm 97
October 15, 2016
PARADIGM DEFINED:
1) an outstandingly clear or typical example or archetype.2) a philosophical and theoretical framework of a scientific school or discipline within which theories, laws, and generalizations, and the experiments performed in support of them, are formulated.
Our website...... http://paradigm97.blogspot.com/ Please copy, paste, and bookmark it.
MISSION STATEMENT
Our website...... http://paradigm97.blogspot.com/ Please copy, paste, and bookmark it.
MISSION STATEMENT
We believe that nurses need each other for support during the "lean and mean" days to help survive them. We offer research results and other ideas to enrich the nursing experience.
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SNIPPET (FROM A MEMBER)
This SNIPPET article is from Jenxl (Linda)and about the group she belongs to called PINCC.org :
Ever wish you could travel AND help others? You’re a nurse or you wouldn’t be reading this. How could you not think this way? RN is such a great ticket as I have said to so many young men & women. It certainly has been for me. I’ve been to Venezuela with Rotaplast, Guatemala a dozen times with various organizations, South America to help a lady have a baby, etc etc but the latest I want to share with you and give you a nudge to look into it further is PINCC. (Prevention International No Cervical Cancer) Check it out at www.PINCC.org .
While the doctors and nurses were being trained by our doctors, I was doing intake interviews. While the patients were being seen we educated the waiting women. Cervical cancer is the #1 killer of women 20-50 in 3rd world countries.

Wouldn’t you like to help change that? You can!!
As with any mission project the participants need to be flexible and do whatever it takes to get the job done. Nurses are good at that. You would be good at that. If after looking at the website you have other questions, please feel free to contact me via email at Jenxl@aol.com. If interested in who I am check out my www.birthprep.com . Click on my name, Linda Jenkins on the home page and you will be taken to my bio which will tell of some of the many places I’ve been able to go because I am a RN. I’d love to hear from you."
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EDITORIAL COLUMN
This month's newsletter won't be as long as usual. I was evacuated and spent over 7 hours on the road trying to get to a safe place. Then spent a lot of the time while waiting, worrying whether or not I would have anything to return to. Fortunately, all is well, but I am sleeping a lot and doing next to nothing each day.
I am just now getting my energy back.
So, please bear with me. Frankie
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INTERESTING READING
Please remember that the REUTERS articles are usually good for only 30 days
U.S. Life Expectancy Lags Behind Other Wealthy Nations
The average life expectancy of men and women in the US, at 76.7 and 81.5, respectively, in 2015 fell below average life expectancy in wealthy countries overall, where men lived an average of 78.1 years and women averaged 83.4 years, according to a report in The Lancet. Average years of good health in the US was also lower than for high-income countries overall, with smoking, diabetes and drug abuse among the top contributors to poor health and early mortality in the US. ...
HealthDay News (10/6)
https://consumer.healthday.com/diabetes-information-10/misc-diabetes-news-181/u-s-life-expectancy-lags-behind-other-wealthy-nations-715615.html
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CDC continues to build US laboratory capacity to rapidly detect Zika virus infection
The Centers for Disease Control and Prevention (CDC) has purchased approximately $2.5 million in laboratory supplies and equipment in August to enhance U.S. laboratory (lab) capacity to test for Zika virus. These purchases help to ensure that states can meet the growing demand for testing and rapid identification of Zika infection, by providing them with materials that allow them to perform testing for Zika virus infection.
Relatively few labs in the U.S. are certified to test for Zika. As a result, when samples are collected, they often have to be shipped to a local health department lab for testing. If the local health department lab doesn’t currently perform Zika testing, it will coordinate testing and ship the samples to CDC. Depending on the CDC lab’s workload, processing and reporting time of a result may take 2 to 4 weeks.
To help states expand access to Zika testing and reduce the amount of time to receive results, CDC has sent materials to help them expand lab capacity and perform testing to detect both current and recent cases of Zika virus infection. Forty-three states[1]the District of Columbia, Puerto Rico, and nine Department of Defense (DOD) laboratories have received material that allows them to conduct testing for recent Zika infection using a CDC-developed test called the MAC-ELISA. MAC-ELISA tests are intended for use in detecting antibodies that the body makes to fight a Zika virus infection. These antibodies (in this case, immunoglobulin M, or IgM) appear in the blood of a person infected with Zika virus beginning 4 to 5 days after the start of illness and last for about 12 weeks. Labs in 41 of those states, plus the District of Columbia, Puerto Rico, along with five DOD labs, have completed the process required to implement the MAC-ELISA assay test. ... https://www.cdc.gov/media/releases/2016/p0920-zika-lab-capacity.html
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Fatty Acid Binding Protein 4 Tied to Preeclampsia Risk in T1DM A study in Diabetes Care showed that elevated levels of fatty acid binding protein 4 during early pregnancy and in the second trimester put women with type 1 diabetes at a greater likelihood of developing preeclampsia later. UK researchers analyzed 710 women from the Diabetes and Pre-eclampsia Intervention Trial and found an independent association between high levels of FABP4 in the second trimester of pregnancy and preeclampsia. Amy C. Wotherspoon, from Queen's University in Belfast, U.K., and colleagues measured serum FABP4 in 710 women from the Diabetes and Pre-eclampsia Intervention Trial in early pregnancy (median 14 weeks of gestation) and in the second trimester (median 26 weeks of gestation).
The researchers found that in women in whom preeclampsia later developed, FABP4 was significantly elevated in early pregnancy and the second trimester (both P < 0.001). There was an independent association for elevated second-trimester FABP4 level with preeclampsia (odds ratio, 2.87; P = 0.03). At both time points, the addition of FABP4 to established risk factors significantly improved net reclassification improvement, and integrated discrimination improvement in the second trimester. http://www.doctorslounge.com/index.php/news/pb/66646
DoctorsLounge.com/HealthDay News (9/21)
DoctorsLounge.com/HealthDay News (9/21)
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FDA approves first drug for Duchenne muscular dystrophy- Drug Information Update The U.S. Food and Drug Administration today approved Exondys 51 (eteplirsen) injection, the first drug approved to treat patients with Duchenne muscular dystrophy (DMD). Exondys 51 is specifically indicated for patients who have a confirmed mutation of the dystrophin gene amenable to exon 51 skipping, which affects about 13 percent of the population with DMD.
Exondys 51 was approved under the accelerated approval pathway, which provides for the approval of drugs that treat serious or life-threatening diseases and generally provide a meaningful advantage over existing treatments. Approval under this pathway can be based on adequate and well-controlled studies showing the drug has an effect on a surrogate endpoint that is reasonably likely to predict clinical benefit to patients (how a patient feels or functions or whether they survive). This pathway provides earlier patient access to promising new drugs while the company conducts clinical trials to verify the predicted clinical benefit.
The accelerated approval of Exondys 51 is based on the surrogate endpoint of dystrophin increase in skeletal muscle observed in some Exondys 51-treated patients. The FDA has concluded that the data submitted by the applicant demonstrated an increase in dystrophin production that is reasonably likely to predict clinical benefit in some patients with DMD who have a confirmed mutation of the dystrophin gene amenable to exon 51 skipping. A clinical benefit of Exondys 51, including improved motor function, has not been established. In making this decision, the FDA considered the potential risks associated with the drug, the life-threatening and debilitating nature of the disease for these children and the lack of available therapy. For more information, please visit: Exondys 51.
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FDA approves Amgen's copy of AbbVie arthritis drug Humira
The U.S. Food and Drug Administration on Friday approved Amgen Inc's biosimilar version of AbbVie's top-selling arthritis drug, Humira.
The drug, Amjevita, known also as adalimumab-atto, was approved to treat rheumatoid arthritis, psoriatic arthritis, Crohn's disease, psoriasis and other conditions.
Amjevita is the fourth biosimilar to be approved by the FDA and is expected to be sold at a discount to the original drug. Last month the agency approved Novartis AG's biosimilar version of Amgen's arthritis drug, Enbrel.
Unlike generics, which are interchangeable with their branded counterparts, biosimilars approved by the FDA to date are not considered interchangeable and therefore are not called generic.
The FDA has determined, however, that there is no clinically meaningful difference between the two products.
In approving the drug the FDA followed the advice of its advisory panel, which in July voted unanimously that the drug was similar in safety and effectiveness to the original.
The approvals come amid a heated national debate about the rising price of prescription drugs. ...
http://www.reuters.com/article/us-amgen-arthritis-biosimilar-idUSKCN11T2JH?feedType=nl&feedName=healthNews&utm_source=Sailthru&utm_medium=email&utm_campaign=US%20Health%20Report%202016-09-26&utm_term=US%20Health%20Report
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2nd Antibiotic Halves C-Section Infection Rate: Study
THURSDAY, Sept. 29, 2016 (HealthDay News) -- Doctors routinely give an antibiotic before a cesarean-section, the surgical delivery of a baby, to prevent infection in the mother. But, a new study suggests that adding a second antibiotic can cut the risk of infection even more.
The researchers found that adding azithromycin to standard antibiotic therapy cut infection rates by 50 percent.
"A simple approach involving the addition of a single dose of azithromycin, a relatively inexpensive and readily available antibiotic, to the recommended standard dose of a single antibiotic such as cefazolin is associated with a markedly lower rate of post-cesarean infection," said senior researcher Dr. William Andrews. He's chairman of the department of obstetrics and gynecology at the University of Alabama at Birmingham.
Cesarean delivery is the most common major surgical procedure performed in the United States. Sixty to 70 percent of these are non-elective, often occurring during labor or because of ruptured membranes, Andrews said. ... https://medlineplus.gov/news/fullstory_161230.html
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Tx Failure Up for High-Flow Therapy Versus CPAP in Preemies Significantly higher rate of treatment failure than CPAP in preterm infants with respiratory distress
A study in The New England Journal of Medicine found that 25.5% of preterm infants with early respiratory distress who had high-flow therapy as primary support had treatment failure, compared with 13.3% of those who received continuous positive airway pressure. However, the findings, based on an international, multicenter, non-inferiority trial involving 564 babies born at 28 weeks of gestation or later, didn't show significant differences in the rates of intubation within 72 hours and adverse events between both groups.
Physician's Briefing/HealthDay News (9/22) http://www.physiciansbriefing.com/Article.asp?AID=715068
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Thank you, Barbara (BAcello) for this article.
Falls are leading cause of injury and death in older Americans
Every second of every day in the United States an older adult falls, making falls the number one cause of injuries and deaths from injury among older Americans.
In 2014 alone, older Americans experienced 29 million falls causing seven million injuries and costing an estimated $31 billion in annual Medicare costs, according to a new report published by the Centers for Disease Control and Prevention in this week’s Morbidity and Mortality Weekly Report (MMWR).
The new numbers are being released in conjunction with the 9th Falls Prevention Awareness Day, sponsored by the National Council on Aging (NCOA). The observance addresses the growing public health issue and promotes evidence-based prevention programs and strategies to reduce the more than 27,000 fall deaths in older adults each year.
“Older adult falls are increasing and, sadly, often herald the end of independence,” said CDC Director Tom Frieden, M.D., M.P.H. “Healthcare providers can make fall prevention a routine part of care in their practice, and older adults can take steps to protect themselves.”
https://www.cdc.gov/media/releases/2016/p0922-older-adult-falls.html
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Study finds Zika infects neural cells related to skull formation
The Zika virus causing an epidemic in Brazil and spreading through the Americas can infect and alter cells in the human nervous system that are crucial for formation of bones and cartilage in the skull, a study found on Thursday.
The research, published in the journal Cell Host & Microbe, may help explain why babies children born with to mother who have had the virus can have smaller-than-average skulls and disproportionate facial features.
Zika has already been shown to attack foetal brain cells known as neural progenitor cells - a type of stem cell that gives rise to various kinds of brain cells.
The death of these cells is what disrupts brain development and leads to microcephaly, the severe birth defect seen in babies whose mothers were infected with Zika during pregnancy.
American scientists who conducted this latest study by infecting human cells with Zika in the lab, found the virus can infect another type of cell known as cranial neural crest cells - which give rise to skull bones and cartilage - and cause them to secrete signaling molecules that alter their function. ...
http://www.reuters.com/article/us-health-zika-skull-idUSKCN11Z2CN?feedType=nl&feedName=healthNews&utm_source=Sailthru&utm_medium=email&utm_campaign=US%20Health%20Report%202016-09-30&utm_term=US%20Health%20Report
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1st Baby Born With DNA From 3 Parents
TUESDAY, Sept. 27, 2016 (HealthDay News) -- A now 5-month-old baby boy is the first worldwide to be born using a controversial technique that combines DNA from three people -- two women and a man.
As reported Tuesday by New Scientist magazine, the technique is designed to help couples who carry rare genetic mutations have healthy children. It has only been legally approved for use in the United Kingdom.
According to the report, the boy was born to a Jordanian couple in which the woman carries genes for Leigh syndrome, a lethal nervous system disorder. The DNA for the illness resides in the cell's energy source, the mitochondria. Mitochondrial DNA is only passed down to children via mothers.
The woman in this case was herself healthy but had already had two children who later died of Leigh syndrome, New Scientist reported.
https://medlineplus.gov/news/fullstory_161176.html
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'Entitled' People May Be Pursuing an Unhappy Path
THURSDAY, Sept. 29, 2016 (HealthDay News) -- "Entitled" individuals who feel superior to others often end up unhappy when reality fails to match their expectations, new research shows.
"Entitlement is a broad construct, but basically it refers to a desire to get something for nothing," explained study lead author Joshua Grubbs, assistant professor of psychology at Bowling Green State University in Ohio.
According to Grubbs, entitlement is a personality trait where a person has an exaggerated belief that he or she is an exception to the rule -- much more deserving of life's blessings that others.
But the new review of more than 170 studies on the subject suggests that entitled folk are also especially vulnerable to disappointment.
And when disappointment strikes, it can mean anger, blaming others, social strife, collapsed relationships and depression, Grubbs' team said.
That's because entitlement is "really an attitude of 'deservingness', without any consideration for earning those things you want," said Grubbs, who conducted the review while a graduate student in psychology at Case Western Reserve University in Cleveland. "I often describe it as someone saying, 'I exist, therefore I deserve whatever I want.' " ... https://medlineplus.gov/news/fullstory_161229.html
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Task force advises routine preeclampsia screening in pregnancy
Reuters Health) - Pregnant women should get routine blood pressure checks at every prenatal visit to screen for preeclampsia, according to new proposed U.S. guidelines aimed at preventing deaths from this complication.
Even though many doctors already monitor blood pressure throughout pregnancy, the U.S. Preventive Services Task Force (USPSTF), a government-backed panel of independent physicians, is updating its clinical guidelines for the first time since 1996 to reflect emerging evidence on the best way to detect preeclampsia.
“The Task Force recognizes the seriousness of this condition, which can progress quickly and become severe, and we continue to recommend pregnant women get screened for preeclampsia,” task force member Dr. Maureen Phipps, a women’s health researcher at Brown University in Providence, Rhode Island, said by email. ...
http://www.reuters.com/article/us-health-pregnancy-preeclampsia-uspstf-idUSKCN11X26K
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FDA approves Medtronic's 'artificial pancreas' for diabetes
Medtronic Plc won U.S. approval on Wednesday for an "artificial pancreas" that is the first device to automatically deliver the right dose of insulin to patients with type 1 diabetes, freeing them from continually monitoring insulin levels throughout each day.
The U.S. Food and Drug Administration, in its approval of the device, the MiniMed 670G, hailed it as a breakthrough.
The device offers type 1 diabetics "greater freedom to live their lives without having to consistently and manually monitor baseline glucose levels and administer insulin," Dr. Jeffrey Shuren, director of the FDA's medical device division, said in a statement.
Analysts said the FDA approved the device six months sooner than expected. However, it will not be available until the spring of 2017.
The MiniMed 670G is the first device that allows a glucose sensor to communicate with an insulin pump and automatically regulate the insulin flow. The device is approved for those aged 14 and older.
The device measures glucose levels every five minutes and automatically administers insulin as needed. Patients will still need to instruct the device to deliver extra insulin for meals and notify the device when they exercise - which lowers glucose levels. ...
http://www.reuters.com/article/us-health-diabetes-medtronic-idUSKCN11Z04Y?feedType=nl&feedName=healthNews&utm_source=Sailthru&utm_medium=email&utm_campaign=US%20Health%20Report%202016-09-29&utm_term=US%20Health%20Report
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FACTS:
Oklahoma has more manmade lakes than any other state, and has over one million surface acres of water.
Four is the only number that has the same amount of letters as its actual value.
New parents will lose 400 to 750 hours of sleep in their baby's first year.
California, Virginia, Pennsylvania, New York, and Texas are the five states with the most reported hauntings.
The dinosaurs became extinct before the Rockies or the Alps were formed.
The last execution by hanging in the U.S. was on January 25, 1996.
The ancient Celts were the first to ferment and distill grains into whiskey. They called it water of life.
About one-third of Spongebob Squarepants fans are adults.Alcohol doesn't kill brain cells, it just causes them
to grow slower.
Harry Truman was the last president to lack a college degree.
There are more head and spinal injuries from cheerleading than all other high school and college sports combined.
Half of All Type 1 Diabetes Develops After 30 Years of Age
MUNICH — Onset of type 1 diabetes is just as likely to occur in people older than 30 years of age as in those younger, new research shows.
The data were presented September 16, 2016, here at theEuropean Association for the Study of Diabetes (EASD) 2016 Annual Meeting by Dr Nicholas JM Thomas, of the Institute of Biomedical and Clinical Science, University of Exeter Medical School, United Kingdom.
Obtained using genetic data from the UK Biobank, the startling results refute the long-held belief that type 1 diabetes is primarily a "juvenile" condition.
Clinically, the findings are particularly relevant for primary care, where people who develop autoimmune-mediated diabetes in adulthood are often misdiagnosed as having type 2 and prescribed metformin instead of insulin. http://www.medscape.com/viewarticle/869028
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New Low-Cost Surgical Tool Could Help Patients in Third World
Two-thirds of the world’s population—some five billion people—lack access to safe, affordable surgical care.
An $85 device conceived in a sock drawer could help change that.
John Langell, a surgeon who runs the University of Utah’s Center for Medical Innovation, had the idea when he was called in for an emergency late one night and used his iPhone flashlight to look for clothes without waking his wife. “I thought, ‘Wow, this is as bright as a laparoscope,’ ” he recalls.
Dr. Langell passed the thought on to students in his bio-innovation class who were looking for a project: Why not build a low-cost laparoscope using cellphone parts and bring minimally invasive surgery to regions of the world that can’t afford it?
http://www.wsj.com/articles/new-low-cost-surgical-tool-could-help-patients-in-third-world-1474855620
Sick Children Face Potentially Deadly Danger: Medication Errors Nurses have important roles in pediatric patient safety and working with families to help ensure children get the right medicines and dosages once they leave the hospital. Medication safety nurse Jamie Irizarry at the Children's Hospital of Philadelphia helped create a safety sheet for parents that shows different versions of ibuprofen, and nurse practitioner Jamie Harris created a kit for storing medicines at home that has instructions and dosages for parents.
http://www.wsj.com/articles/sick-children-face-potentially-deadly-danger-medication-errors-1474855500
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Half of All Type 1 Diabetes Develops After 30 Years of Age
The data were presented September 16, 2016, here at the European Association for the Study of Diabetes (EASD) 2016 Annual Meeting by Dr Nicholas JM Thomas, of the Institute of Biomedical and Clinical Science, University of Exeter Medical School, United Kingdom.
Obtained using genetic data from the UK Biobank, the startling results refute the long-held belief that type 1 diabetes is primarily a "juvenile" condition.
Clinically, the findings are particularly relevant for primary care, where people who develop autoimmune-mediated diabetes in adulthood are often misdiagnosed as having type 2 and prescribed metformin instead of insulin. The UK study
http://www.medscape.com/viewarticle/869028
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Could Prescribed NSAID Painkillers Raise Heart Failure Risk?
A case-control study in The BMJ found patients who used prescription nonsteroidal anti-inflammatory drugs within the preceding 14 days had a 19% higher relative risk of hospital admission for heart failure, compared with those who used the drugs more than about six months in the past. The findings, based on medical records for over 92,000 hospital admissions for heart failure and about 8.2 million controls, identified nine drugs particularly linked to an increased heart failure risk and found a greater risk with very high doses of certain drugs.
That risk increases with the amount of NSAIDs a person is taking, said study author Andrea Arfe, a Ph.D. student at University of Milano-Bicocca, in Italy.
A person's risk of hospitalization for heart failure doubles for some NSAIDs used at very high doses, including diclofenac (Cataflam or Voltaren), etoricoxib (Arcoxia), indomethacin (Indocin), and piroxicam (Feldene), Arfe said.
Also, "our findings -- which focused only on prescription NSAIDs -- might apply to over-the-counter NSAIDs as well," Arfe said. "Although over-the-counter NSAIDs are typically used at lower doses and for shorter durations, they are sometimes available at the same doses as prescription NSAIDs and they may be inappropriately overused." ...
https://consumer.healthday.com/circulatory-system-information-7/heart-failure-news-753/could-nsaid-painkillers-raise-heart-failure-risk-715312.html
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More U.S. babies born addicted to opiates like heroin
(Reuters Health) - The proportion of U.S. babies born suffering from withdrawal syndrome after exposure to heroin or prescription opiates in utero has more than doubled in less than a decade, a study suggests.
Researchers focused on what’s known as neonatal abstinence syndrome, a condition akin to withdrawal that develops when babies essentially become addicted to drugs their mothers use during pregnancy.
Nationally, the rate of neonatal abstinence syndrome involving mothers’ use of opiates - which includes heroin as well as prescription narcotics like codeine and Vicodin - surged from 2.8 cases for every 1,000 births in 2009 to 7.3 cases for every 1,000 births in 2013, the study found.
At least some of this surge in the case count is due to drug policies designed to crack down on prescription drug abuse and combat the methamphetamine epidemic, said lead study author Dr. Joshua Brown, a pharmacy researcher at the University of Kentucky in Lexington. ...
http://www.reuters.com/article/us-health-newborns-opiate-addiction-idUSKCN11W2J8?feedType=nl&feedName=healthNews&utm_source=Sailthru&utm_medium=email&utm_campaign=US%20Health%20Report%202016-09-27&utm_term=US%20Health%20Report
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Exercise Speeds Seniors' Recovery From Disability
MONDAY, Sept. 26, 2016 (HealthDay News) -- Elderly adults who regularly exercise are less likely to suffer a disability -- and if they do, they tend to recover faster, a new clinical trial finds.
Researchers found that when they got sedentary older adults into an exercise routine, it curbed their risk of suffering a disabling injury or illness. And those who did develop a physical disability were one-third more likely to recover from it, compared to seniors who remained sedentary.
Experts said the findings underscore an important message: It's never too late to reap the benefits of exercise.
"And it doesn't have to be some heavy-duty regimen. You don't have to join a gym," said Patricia Katz, a professor of medicine at the University of California, San Francisco.
In this study, she pointed out, moderate walking was the main activity.
Katz wrote an editorial published online with the study Sept. 26 in Annals of Internal Medicine.
It's well-known that regular exercise can have a range of health benefits, including lower risks of heart disease, diabetes, certain cancers and depression....
https://medlineplus.gov/news/fullstory_161157.html
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Fact: Regarded as the fastest snake in the world, the Black Mamba can move at 17.6 feet per second and reach amazing speeds of 12 mph. The Black Mamba is not only the fastest snake in terms of moving, but it is also one of the fastest striking snakes in the world. The Black Mamba is regarded as the most feared snake in Africa, where its bite is known as the “Kiss of death”. A single bite contains enough venom to kill ten people. The Black Mamba’s extraordinary speed, combined with its fast-striking venom, make it one of the world’s most deadly snakes. *******************
A Mighty Girl Pick of the Day:
“Sophie Scholl: The Final Days”
directed by Marc Rothemond. This powerful film tells the true story of Germany’s most famous anti-Nazi heroine, Sophie Scholl. At the height of the Third Reich’s control of Germany, 21-year-old Sophie Scholl, her brother, and other students in Munich form a resistance group called The White Rose and distribute anti-Nazi literature. Before long, they are arrested and interrogated in preparation for a show trial. This tense interrogation between Scholl and Nazi interrogator Robert Mohr about questions of freedom and personal responsibility lies at the heart of the film.
From every argument between Scholl and Mohr, distilled from historical records, to the tension of her trial, the film gives a stunning account of Scholl’s final six days before her execution. This moving and challenging film, which received an Oscar nomination for the Best Foreign Language Film in 2005, is an excellent way to introduce teens to the bravery and perseverance of those who resisted the Nazi regime, as well as to encourage discussion on larger questions of individual responsibility in the face of tyranny. Highly recommended for both adults and teens 13 and up.
To learn more or order “Sophie Scholl: The Final Days”, visit http://www.amightygirl.com/sophie-scholl-the-final-days -- or you can stream the film online at http://amzn.to/1Rr91ug
For those who would like to learn more about Sophie's story, there are also several books for adult readers about her life and the White Rose: "Sophie Scholl and the White Rose" (http://amzn.to/1pEAtXb), "The White Rose: Munich, 1942-1943" (http://amzn.to/1jnUEZu), and "A Noble Treason" (http://amzn.to/1GUStoC).
For an inspiring book about more true stories of courageous women heroes of WWII, check out "Women Heroes of World War II: 26 Stories of Espionage, Sabotage, Resistance, and Rescue" for ages 13 and up athttp://www.amightygirl.com/women-heroes-of-world-war-ii
And, for books for both children and teens about girls and women who lived during the Holocaust period, including stories of other heroic resisters and rescuers, check out our post for Holocaust Remembrance Week at http://www.amightygirl.com/blog?p=11586
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QUIZ TIME
Which of the following meets the requirements of organ dysfunction for severe sepsis?
a. An acute lung injury with Pao2/Fio2 < 250 mm Hg with pneumonia as infection source.
b. An acute lung injury with Pao2/Fio2 < 250 mm Hg without pneumonia as infection source.
b. An acute lung injury with Pao2/Fio2 < 250 mm Hg without pneumonia as infection source.
c. A normal lactate level.
d. A reduced lactate level.
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How much a decade of obesity raises your cancer risk A longitudinal study in the journal PLOS Medicine found women had a 10% increased risk of developing breast, endometrial, kidney or colon cancer for every 10 years of being obese and a 7% greater risk for every decade of being overweight. The findings, based on 73,913 women in the US who were enrolled in the Women's Health Initiative, also showed that the risk of obesity-related cancers depended on the degree of overweight.
It's the first study to explore the relationship between overweight duration and cancer risk in a large cohort of women, said Melina Arnold, a scientist at the World Health Organization's International Agency for Research on Cancer and lead author of the study.
"Given the result from previous studies supporting the overall link between obesity and cancer, our results are in line with what we know about this relationship," Arnold said. "Yet it adds to current scientific evidence by suggesting that there seems to be a cumulative effect of obesity on cancer risk." ...
CNN (8/16), HealthDay News (8/16) http://www.cnn.com/2016/08/16/health/obesity-overweight-cancer-risk/
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Old heart device wires tied to complications, death risk
(Reuters Health) - Patients with pacemakers and defibrillators are about twice as likely to have minor and life-threatening complications when having them removed if old wiring was left behind in earlier procedures to replace or upgrade devices, a U.S. study suggests.
Researchers analyzed data on surgery outcomes for 1,386 patients having devices removed because of infections, including a subset of 323 people who had abandoned leads – the wires that deliver energy from pacemakers and defibrillators to the heart muscle.
Doctors were unable to remove the devices and all of the leads without serious complications in 13 percent of patients who had abandoned wires, compared to a 3.7 percent failure rate for patients who didn’t have abandoned leads.
“Device infection is a very serious life threatening condition with a 66 percent risk of death if left untreated,” said senior study author Dr. Oussama Wazni, an electrophysiology researcher at Cleveland Clinic in Ohio. ...
http://www.reuters.com/article/us-health-cardiacdevices-abandoned-leads-idUSKCN11Y2ZI?feedType=nl&feedName=healthNews&utm_source=Sailthru&utm_medium=email&utm_campaign=US%20Health%20Report%202016-09-29&utm_term=US%20Health%20Report
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Smoking leaves chemical traces on DNA
(Reuters Health) - Tobacco smoke leaves its mark on DNA by changing a chemical code on the DNA molecule that can sometimes change gene activity, according to a new study.
Some of these molecular changes revert to their original state when a smoker quits, but others persist in the long term, the researchers found.
Experts have known for some time that smoking causes changes of the DNA molecule, but they are now learning more about how widespread the changes are, and what they may mean, said senior author Dr. Stephanie J. London, chief of the Epidemiology Branch at the National Institute of Environmental Health Sciences in Research Triangle Park, North Carolina.
“We don’t really know whether it means ‘damage’ to the DNA,” London told Reuters Health. “That requires more study, using data outside what we have here. What we’re saying is that it’s a change to your DNA that can have a downstream effect on what genes are expressed at what levels.”
The researchers combined data from 16 sets of participants in a previous study of aging, totaling more than 15,000 people who had provided blood samples that were analyzed for a type of DNA change known as methylation.
The DNA molecule contains instructions for growth and development in the form of genes, and so-called methyl groups along the molecule's surface - collections of hydrogen and carbon atoms - can determine which genes get activated.
The study team compared 2,433 current smokers - those who said they smoked at least once a day sometime over the last year - to 6,518 former smokers who had stopped at least one year before the blood draw and 6,596 never smokers. ...
http://www.reuters.com/article/us-health-smoking-dna-idUSKCN11R2UV?feedType=nl&feedName=healthNews&utm_source=Sailthru&utm_medium=email&utm_campaign=US%20Health%20Report%202016-09-22&utm_term=US%20Health%20Report
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ANIMAL FACTS:
An elephant's trunk has more than 40,000 muscles. In comparison a human being only has 639 muscles total.
When a crow dies, the other crows investigate if there's a threat where the death occurred, so they can avoid it in the future.
All pandas in the world are on loan from China.
Octopus skin can change color 177 times an hour.
The estimated number of dinosaur species that existed in the Mesozoic era is between 1,543 and 2,468 species.
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HUMOR SECTION
*examination of genitalia reveals that he is circus-sized.
*indwelling urinary catheter draining clear yellow roses.
*examination of genitalia was completely negative except for the right foot.
*pelvic examination to be done later on the floor.
*indwelling catheter draining large amount of urine the color of american beer.
*md at bedside attempting to urinate. unsuccessful. (the physician was actually attempting to intubate).
social history
*the patient lives at home with his mother, father and pet turtle, who is presently enrolled in day care three times a week.
*patient was in his usual state of good health until his airplane ran out of gas and crashed.
*examination reveals a well-developed male lying in bed with his family in no distress.
miscellaneous
*the skin was moist and dry.
*both breasts are equal and reactive to light and accomodation.
*the baby was delivered; the cord clamped and cut and handed to the pediatrician, who breathed and cried immediately.
*skin: somewhat pale, but present.
*i saw your patient today, who is still under our car for physical therapy.
*because she can't get pregnant with her husband. i thought you'd like to work her up.
*the test indicated abnormal lover function.
*if he squeezes the back of his neck for 4 or 5 years, it comes and goes.
*discharge status: alive, but without permission.
*indwelling urinary catheter draining clear yellow roses.
*examination of genitalia was completely negative except for the right foot.
*pelvic examination to be done later on the floor.
*indwelling catheter draining large amount of urine the color of american beer.
*md at bedside attempting to urinate. unsuccessful. (the physician was actually attempting to intubate).
social history
*the patient lives at home with his mother, father and pet turtle, who is presently enrolled in day care three times a week.
*patient was in his usual state of good health until his airplane ran out of gas and crashed.
*examination reveals a well-developed male lying in bed with his family in no distress.
miscellaneous
*the skin was moist and dry.
*both breasts are equal and reactive to light and accomodation.
*the baby was delivered; the cord clamped and cut and handed to the pediatrician, who breathed and cried immediately.
*skin: somewhat pale, but present.
*i saw your patient today, who is still under our car for physical therapy.
*because she can't get pregnant with her husband. i thought you'd like to work her up.
*the test indicated abnormal lover function.
*if he squeezes the back of his neck for 4 or 5 years, it comes and goes.
*discharge status: alive, but without permission.
~**~**~~**~~**~~**~~**~~
CEU SITES---(CME and CNE)
Those that are-----Free and Otherwise..........Go to www.sharedgovernance.org for access to a free continuing education module about shared governance, written by Robert Hess, Forum’s founder, and Diana Swihart, Forum advisory board member.
Please follow me on Twitter as Dr Robert Hess. info@sharedgovernance.orgwww.sharedgovernance.org
Please follow me on Twitter as Dr Robert Hess. info@sharedgovernance.orgwww.sharedgovernance.org
Pay Only $34.99 for a full year of CONTACT HOURS
www.nurse.com for CNE offerings.
www.nurse.com for CNE offerings.
Free CEs http://www.myfreece.com/welcome.asp
THESE ARE NEW CEs
|
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WEBSITES/ LINKS
Always on the lookout for interesting websites / links. Please send them to: RNFrankie@AOL.com.
This is an excellent nursing site, check it out:http://nursingpub.com/
If you're buying a used car, it is recommended having a mechanic inspect it first. And screen the car's VIN through the free database at carfax.com/flood
Rozalfaro's website: http://www.alfaroteachsmart.com/articles.htm
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*
MEDICAL RECALLS
*
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Sterile Products by Wells Pharmacy Network: Recall - Concern for Lack of Sterility Assurance
Wells Pharmacy Network is voluntarily recalling all sterile human and veterinary products prepared between February 22, 2016 and September 14, 2016, and that remain within expiry due to FDA concern over a lack of sterility assurance. See the press release for a listing of affected prodcuts and lot numbers.
Administration of a drug product intended to be sterile that has microbial contamination may result in infections that may be serious and life-threatening.
BACKGROUND: The recalled products were used for a variety of indications. No vial or portion of any lot of these medications has been found to be non sterile. All recalled products have a label that includes the name Wells Pharmacy Network, logo, drug name, and expiration date. If unsure, customers can call the pharmacy to determine if their product is on the list. To date, no adverse events have been reported. Read the MedWatch safety alert, including a link to the press release, at:
http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm522103.htm
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ADVERTISEMENTS
from the members
This ad is from Decubqueen (Gerry)..........AccuRuler Accurate wound measurement designed by nurses, for nurses. Now carrying wound care and first-aid supplies at prices you can afford.
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NEW MEMBERS
Please send the prospective members' screen names and first names to me: RNFrankie@AOL.com
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NOTICE:
I attempt to send newsletters to your email addresses on file and if the newsletters are rejected THREE consecutive times, I must then delete the email address until you contact me with an updated email address. So, be certain to let me know when you change your address. RNFrankie@AOL.com
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EDITORIAL STAFF:
GingerMyst @AOL.com (Anne), GALLO RN @AOL.com (Sue), HSears9868 @AOL.com (Bonnie), Laregis @AOL.com (Laura), Mrwrn @AOL.com (Miriam), and Schulthe @AOL.com (Susan)
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PARADIGM 97 CO-FOUNDERS:
MarGerlach @AOL.com (Marlene) and RNFrankie @AOL.com (Frankie)
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DISCLAIMER: The intent of this PARADIGM BYTES Newsletter is to provide communication and information for our members. Please research the hyperlinks and information provided by our members. The articles and web sites are not personally endorsed by the editors, nor do the articles necessarily reflect the staff's views.
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THOUGHT FOR THE DAY
"There is no distinct American criminal class,
except for Congress"
Mark Twain
Hope to hear from you..... Frankie
Correct answer: b. Patients with severe sepsis have organ dysfunction as indicated by acute lung injury with Pao2/Fio2 < 250 mm Hg without pneumonia as infection source, acute lung injury with Pao2/Fio2 < 200 mm Hg with pneumonia as infection source, and an elevated lactate level.
To learn more, read the continuing nursing education article Nurses can help improve outcomes in severe sepsis
To learn more, read the continuing nursing education article Nurses can help improve outcomes in severe sepsis
